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Come April 29, the Santa Clara Convention Center will once again become the epicentre of Silicon Valley’s startup and AI ecosystem as TiEcon 2026 brings together founders, investors, and technologists from around the world.
This year’s theme — “AI & You: Human Centered, AI Powered” — reflects a sharper reality for the AI era: less experimentation, more execution; less hype, more measurable enterprise impact.
Scheduled from April 29 to May 1, 2026, the three-day conference is expected to draw entrepreneurs, venture capitalists, enterprise leaders, researchers, and students for one of the most concentrated global gatherings focused on AI and entrepreneurship.
The agenda spans 80+ sessions across 8+ thematic tracks, including:
A defining focus this year is Applied AI, where discussions move beyond models and capabilities to real-world deployment, ROI, and enterprise-scale adoption — reflecting the industry’s shift from innovation to implementation.
The speaker lineup underscores this positioning, featuring two Nobel Laureates — Dr. John M. Martinis and Dr. Randy Schekman — alongside senior leaders from Microsoft, Meta, NVIDIA, and the University of California system.
Beyond keynotes, TiEcon 2026 continues to push execution-oriented programming, including hands-on workshops such as the NVIDIA AI Bootcamp, Startup Bootcamp, VC Connect, and GTM for AI sessions, aimed at helping founders translate technology into scalable businesses.
While the programming anchors the event, TiEcon’s real gravity remains its network effect — the investor-founder interactions, enterprise collaborations, and deal-making conversations that define Silicon Valley’s innovation cycle.
Three-plus decades of impact
TiEcon is the flagship global conference of TiE Silicon Valley (TiE SV), part of The IndUS Entrepreneurs (TiE) — a non-profit founded in 1992 by Indian-American entrepreneurs, executives, and professionals. Today, TiE operates across 60+ chapters in 17 countries, making it one of the world’s largest entrepreneurship ecosystems.
For more than three decades, TiE has evolved into a foundational platform for entrepreneurship — built around mentoring, networking, education, incubation, and capital access.
Under the leadership of Anita Manwani (President and Board Chair, TiE Silicon Valley), alongside Ajay Manglani (COO, TiE Silicon Valley), the organisation has scaled its programming to nearly 100 initiatives annually, supporting founders across idea, growth, and scale stages.
Often referred to as the “world’s original startup accelerator,” TiE Silicon Valley continues to leverage its deep corporate and investor network to accelerate startup growth and market access.
Over the years, TiE has:
With its 2026 edition, TiEcon reinforces its positioning not just as a conference, but as a live signal of where AI, capital, and entrepreneurship are converging — and where the next generation of companies is being defined.
This year’s theme — “AI & You: Human Centered, AI Powered” — reflects a sharper reality for the AI era: less experimentation, more execution; less hype, more measurable enterprise impact.
Scheduled from April 29 to May 1, 2026, the three-day conference is expected to draw entrepreneurs, venture capitalists, enterprise leaders, researchers, and students for one of the most concentrated global gatherings focused on AI and entrepreneurship.
The agenda spans 80+ sessions across 8+ thematic tracks, including:
- Applied AI & Enterprise Transformation
- Go-To-Market in the AI Era
- Cybersecurity & Trust in AI Systems
- Healthcare & BioAI
- Mobility & Robotics
- Retail, Commerce & Supply Chains
- Climate & Sustainability
- Global Investment, Policy & Talent
A defining focus this year is Applied AI, where discussions move beyond models and capabilities to real-world deployment, ROI, and enterprise-scale adoption — reflecting the industry’s shift from innovation to implementation.
The speaker lineup underscores this positioning, featuring two Nobel Laureates — Dr. John M. Martinis and Dr. Randy Schekman — alongside senior leaders from Microsoft, Meta, NVIDIA, and the University of California system.
Beyond keynotes, TiEcon 2026 continues to push execution-oriented programming, including hands-on workshops such as the NVIDIA AI Bootcamp, Startup Bootcamp, VC Connect, and GTM for AI sessions, aimed at helping founders translate technology into scalable businesses.
While the programming anchors the event, TiEcon’s real gravity remains its network effect — the investor-founder interactions, enterprise collaborations, and deal-making conversations that define Silicon Valley’s innovation cycle.
Three-plus decades of impact
TiEcon is the flagship global conference of TiE Silicon Valley (TiE SV), part of The IndUS Entrepreneurs (TiE) — a non-profit founded in 1992 by Indian-American entrepreneurs, executives, and professionals. Today, TiE operates across 60+ chapters in 17 countries, making it one of the world’s largest entrepreneurship ecosystems.
For more than three decades, TiE has evolved into a foundational platform for entrepreneurship — built around mentoring, networking, education, incubation, and capital access.
Under the leadership of Anita Manwani (President and Board Chair, TiE Silicon Valley), alongside Ajay Manglani (COO, TiE Silicon Valley), the organisation has scaled its programming to nearly 100 initiatives annually, supporting founders across idea, growth, and scale stages.
Often referred to as the “world’s original startup accelerator,” TiE Silicon Valley continues to leverage its deep corporate and investor network to accelerate startup growth and market access.
Over the years, TiE has:
- Influenced over $1 trillion in wealth creation
- Helped generate more than 2 million jobs
- Built a community of 40,000+ members
- Supported 25,000+ startups globally
- Helped shape early trajectories of leaders such as Kirthiga Reddy, former SoftBank Vision Fund partner
With its 2026 edition, TiEcon reinforces its positioning not just as a conference, but as a live signal of where AI, capital, and entrepreneurship are converging — and where the next generation of companies is being defined.
