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US & Iran To Hold 2nd Round Of Direct Talks In Islamabad On April 21
24htopnews | April 21, 2026 1:08 PM CST

US and Iran are set to hold a second round of direct talks on April 21 in Islamabad, Pakistan. The US delegation will be led by Vice President JD Vance, while Iran will be represented by Speaker Mohammad-Bagher Ghalibaf and FM Abbas Araghchi. Reports say Vance and the US team are still in the US but are expected to travel to Pakistan soon for the negotiations.

The United States and Iran delegations are set to hold a second round of direct negotiations on April 21 (Tuesday) in Islamabad, Pakistan, according to reports. The US side will be led by Vice President JD Vance, while the Iranian delegation will be headed by Speaker of the Parliament Mohammad-Bagher Ghalibaf and Foreign Minister Abbas Araghchi.

According to reports, Vice President JD Vance is still in the United States and has not yet departed for Islamabad, and neither has the American delegation; however, they plan to travel to Pakistan soon.

Ahead of the second round of US-Iran peace talks, Vice President JD Vance said on April 14 that deep mistrust between the two nations remains the main obstacle in transforming a fragile ceasefire into a broader agreement, even though both sides are willing to keep negotiating.

“This was a meeting that never happened at that level between the US and the Iranian government in 49 years... So there is a lot of mistrust between Iran and the USA and it can't be solved overnight, but I know that the people sitting across wanted to make a deal... We negotiated in good faith... I feel very good about where we are,” he said.


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