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Japanese researchers begin human trials for drug to regrow teeth
NewsBytes | May 2, 2026 9:39 PM CST

USAG-1 antibody spurs tooth regrowth

The science centers around blocking a protein called USAG-1, which usually stops extra teeth from forming.
By using an antibody to turn off USAG-1, scientists got mice to grow extra molars and even helped dogs regrow missing premolars.
Human trials started at Kyoto University Hospital in late 2024 with adults aged 30-64; by April 2026, the results look safe and promising so far.
Next up: they're hoping to test the drug with children born without any teeth — potentially changing how dentists treat tooth loss for good.


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