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Frequent blisters in the mouth are not just stomach upset, learn other reasons in the eyes of doctors
Samira Vishwas | July 21, 2025 11:25 PM CST

Frequent blisters in the mouth are a common but extremely disturbing problem. Many people start treating it by connecting it to “stomach heat” or “digestive disturbances”, but according to experts it can also be a sign of many other health problems.

Dr. explains, “Stomach failure such as acidity or constipation can cause mouth blisters, but this is not the only reason behind it. Frequent or long-to-long blisters can also point to a serious problem in the body.”

Possible causes of blisters:
1. Vitamins and minerals deficiency
Especially vitamin B12, iron and folic acid deficiency can cause mouth blisters repeatedly. This deficiency is caused by a weak diet or disturbances in the absorption of nutrition in the body.

2. Digestive problems
Stomach disorders such as constipation, gas, acidity and irritable bowl syndrome (IBS) are also associated with mouth ulcers.

3. Mental stress and lack of sleep
Constant mental stress, lack of sleep and fatigue also reduce the body’s immunity, which can cause blisters repeatedly.

4. hormonal change or infection
Some women have blisters due to hormonal fluctuations before periods. Apart from this, viral or bacterial infections can also be one of the reasons.

5. Reaction of medicines or toothpaste
Some allergies, NSAIDs drugs or toothpastes with sodium loril sulfate can also cause blisters in the mouth.

When to be cautious?
If blisters stay for more than 2 weeks

Blood starts coming or a lot of pain

There is difficulty in eating and drinking

Weight reduced

What is the solution?
Take balanced and nutritious diet

Drink enough water

Reduce stress

Take a vitamin supplement by checking a doctor

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