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The greatest sibling duos in gaming- The Week
Sandy Verma | August 19, 2025 5:24 PM CST

From side-scrolling RPGs to sprawling third-person epics, sibling relationships have long been an important part of video game history.

These duos don’t just share DNA—they share destinies and rivalries, bringing in an emotional weight that greatly elevates the game’s narrative.

This Raksha Bandhan, here are 6 sibling duos—integral to their respective games—who continue to fascinate gamers.

‘Super Mario Bros.’ – Mario and Luigi


A still from the film adaptation of Super Mario Bros. | Universal Pictures

No sibling pair is more recognisable than Mario and Luigi. The Super Mario Bros. franchise set the gold standard for cooperative gameplay, with Luigi evolving from a lanky sidekick into a beloved hero in his own right through spin-off franchises like the ‘Luigi’s Mansion’ series. Their bond is built on loyalty and pure-hearted teamwork.

‘Devil May Cry’ – Dante and Vergil

Photo: YouTube, Capcom
Photo: YouTube, Capcom

In contrast, paranormal mercenary Dante and his half-demon twin brother Vergil of ‘Devil May Cry’ are torn apart by ambition and philosophy. The twins have clashed multiple times in a rivalry that’s as operatic as it is explosive. What adds layers to their relationship and gives the story depth is the underlying yearning for connection.

‘Assassin’s Creed: Syndicate’ – Jacob and Evie Frye


Photo: X, Ubisoft

Jacob and Evie Frye offer contrasting approaches to revolution: unpredictability and brawn versus stealth and brains. As you switch between them, the game cleverly mirrors the duality found in most real-life siblings.

‘Uncharted 4: A Thief’s End’ – Nathan and Sam Drake

Photo: YouTube, Sony Interactive Entertainment
Photo: YouTube, Sony Interactive Entertainment

Once separated by circumstances, the two brothers bring a cinematic flair to sibling storytelling. Their shared past and dangerous treasure hunts make them one of gaming’s most heartfelt brotherly journeys.

‘Resident Evil’ – Chris and Claire Redfield

Photo: YouTube, Capcom
Photo: YouTube, Capcom

The relationship between Chris and Claire is one primarily motivated by survival. Whether they’re fighting bioweapons or hunting for each other through zombie-infested corridors, the Redfields are an embodiment of resilience through trust.

‘Call of Duty: Ghosts’ – Logan and Hesh Walker

Photo: Activision
Photo: Activision

This fascinating story of brothers bound by war against the Federation involves an unforgettable twist that redefines their relationship, proving that even military shooters can carry emotional weight.

This article is for information purposes alone, and THE WEEK does not endorse any specific game title, studio or console. Please check the appropriate age ratings of each game and play responsibly.


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