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Kidney International study finds promising oral drug for PH2
NewsBytes | April 7, 2026 4:39 PM CST

N-PPG reduced kidney stones in mice

The medication, called N-propargylglycine (N-PPG), blocks an enzyme that triggers excess oxalate production, the main culprit behind PH2.
In mouse studies, those given N-PPG had fewer kidney stones and healthier kidneys than untreated mice.
While more research is needed before it's available for people, this breakthrough could make life a lot easier for those living with PH2.


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